Teneligliptin 20mg and Metformin Hydrochloride 1000mg (SR) Tablets: Uses, Benefits, and Expert Advice
This combination medicine is widely prescribed for managing type 2 diabetes mellitus in adults. It contains two active ingredients: Teneligliptin (20mg) and Metformin Hydrochloride (1000mg) in sustained release (SR) form. The Jan Aushadhi version offers an affordable generic alternative to expensive branded diabetes medications.
Teneligliptin and Metformin Tablet Uses
- Improves blood sugar control in type 2 diabetes when diet and exercise alone are not enough.
- Helps reduce HbA1c levels (average blood sugar over 2-3 months).
- Often used as a second-line therapy when metformin alone does not provide adequate glycemic control.
- May be used in combination with other antidiabetic medicines like sulfonylureas or insulin.
How Teneligliptin and Metformin Works
This combination works through two complementary mechanisms:
- Teneligliptin belongs to the DPP-4 inhibitor class. It increases the levels of incretin hormones (GLP-1 and GIP), which stimulate insulin release from the pancreas in response to meals and reduce glucagon secretion. This helps lower blood sugar after eating.
- Metformin works primarily by decreasing glucose production in the liver, improving insulin sensitivity in muscles and fat tissues, and reducing glucose absorption from the intestines. The sustained release formulation provides a more gradual effect with fewer gastrointestinal side effects.
Together, they address multiple defects in type 2 diabetes: insulin resistance, impaired insulin secretion, and excessive liver glucose output.
Common Side Effects of Teneligliptin and Metformin
While many people tolerate this medicine well, some may experience:
- Gastrointestinal issues: nausea, diarrhea, abdominal discomfort, loss of appetite (more common with metformin, especially at start).
- Hypoglycemia (low blood sugar) – risk increases when combined with other antidiabetic drugs like sulfonylureas or insulin.
- Upper respiratory tract infection, headache, or joint pain (occasional with teneligliptin).
- Metallic taste in mouth (metformin).
- Rare but serious: lactic acidosis (with metformin, especially in kidney impairment), pancreatitis (with DPP-4 inhibitors).
Expert Advice for Teneligliptin and Metformin
- Take this medicine exactly as prescribed by your doctor, usually once or twice daily with meals to reduce stomach upset.
- Do not crush or chew the sustained release tablets; swallow them whole.
- Monitor your blood sugar regularly as advised by your healthcare provider.
- Inform your doctor if you have kidney disease, liver disease, heart failure, or a history of pancreatitis.
- Avoid alcohol while taking metformin as it increases the risk of lactic acidosis.
- If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose.
- This medicine is not for type 1 diabetes or diabetic ketoacidosis.
Jan Aushadhi Price and Availability
The Jan Aushadhi version of Teneligliptin 20mg + Metformin 1000mg SR tablets is available at a highly affordable price of ₹37.50 for a strip of 10 tablets. This is significantly cheaper than branded alternatives, making diabetes management accessible to all. You can find this medicine at any Jan Aushadhi Kendra across India. Always check the packaging for the correct composition and expiry date.
Safety Note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medication. Verify the composition, strength, and suitability of this medicine with your healthcare provider. Do not self-medicate or change your diabetes treatment without medical supervision.