Metformin 1000mg (Prolonged release) and Glimepiride 4mg Tablets IP

Product Details

Unit Size 15's

Jan Aushadhi MRP ₹43.13

Last Updated July 14, 2026

Data Source PMBJP Official Drug Database

Metformin 1000mg (Prolonged release) and Glimepiride 4mg Tablets IP: Uses, How It Works, Side Effects, and Expert Advice

This combination medicine is used to manage type 2 diabetes mellitus when diet, exercise, and single-agent therapy do not provide adequate blood sugar control. It contains two active ingredients: Metformin (1000mg prolonged release) and Glimepiride (4mg).

Uses of Metformin + Glimepiride

Improves glycemic control in adults with type 2 diabetes.
Helps lower blood sugar levels when used alongside lifestyle modifications.
Often prescribed when metformin alone is insufficient.

How Metformin + Glimepiride works

Metformin belongs to the biguanide class and works by decreasing glucose production in the liver, reducing intestinal absorption of glucose, and improving insulin sensitivity. Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin. Together, they address multiple defects in type 2 diabetes.

Common side effects of Metformin + Glimepiride

Hypoglycemia (low blood sugar) – especially if meals are skipped or alcohol is consumed.
Gastrointestinal issues: nausea, diarrhea, stomach upset (more common with metformin).
Weight gain (possible with glimepiride).
Metallic taste (metformin).
Rare but serious: lactic acidosis (metformin) – seek immediate medical help if symptoms like muscle pain, difficulty breathing, or unusual drowsiness occur.

Expert advice for Metformin + Glimepiride

Take this medicine exactly as prescribed, usually once or twice daily with meals to reduce stomach upset.
Monitor blood sugar regularly, especially when starting or adjusting dose.
Do not skip meals; carry a fast-acting sugar source (like glucose tablets or juice) to treat hypoglycemia.
Avoid alcohol as it can increase the risk of lactic acidosis and hypoglycemia.
Inform your doctor about any kidney, liver, or heart conditions before use.
Prolonged-release tablets should be swallowed whole; do not crush or chew.

Jan Aushadhi price and availability

At Jan Aushadhi Kendras, this combination is available at an affordable price of ₹43.13 for 15 tablets (unit size). The generic version offers the same quality and effectiveness as branded alternatives but at a fraction of the cost. Always check the packaging for the correct composition and expiry date.

Safety note

This information is for educational purposes only and does not replace medical advice. Always consult your doctor or pharmacist before starting any new medication. Do not change your dose or stop taking this medicine without professional guidance. If you experience symptoms of hypoglycemia (sweating, dizziness, confusion) or lactic acidosis (muscle pain, rapid breathing), seek immediate medical help.

Known Brand Alternatives

This Jan Aushadhi medicine is a generic equivalent for:

Glycomet GP 4 Glimestar M 4 Amaryl M 4 Zorylin M 4 Glimisave M 4 Glimiprex M 4

Suggested Related Medicines

Frequently Asked Questions

What is the Jan Aushadhi price of Metformin 1000mg + Glimepiride 4mg tablets?

The Jan Aushadhi price for Metformin 1000mg (prolonged release) and Glimepiride 4mg tablets is ₹43.13 for a strip of 15 tablets. This is significantly lower than most branded alternatives.

How should I take Metformin + Glimepiride tablets?

Take this medicine exactly as prescribed by your doctor, usually once or twice daily with meals to reduce stomach upset. Swallow the prolonged-release tablet whole; do not crush or chew. Do not skip meals to avoid low blood sugar.

What are the common side effects of this combination?

Common side effects include hypoglycemia (low blood sugar), nausea, diarrhea, stomach upset, weight gain, and metallic taste. Serious side effects like lactic acidosis are rare but require immediate medical attention.

Can I switch from a branded diabetes medicine to this Jan Aushadhi generic?

Yes, Jan Aushadhi generics contain the same active ingredients in the same strength as branded versions. However, always consult your doctor before switching to ensure it is appropriate for your condition and to adjust the dose if needed.