Mesalazine Prolonged Release Tablets IP 500mg Uses
Mesalazine, also known as 5-aminosalicylic acid (5-ASA), is a medication primarily used to treat inflammatory bowel diseases (IBD), specifically ulcerative colitis and Crohn's disease. It helps to reduce inflammation in the lining of the digestive tract, thereby managing symptoms like abdominal pain, diarrhea, and rectal bleeding. This medicine is often prescribed for both acute flare-ups and maintenance of remission.
How Mesalazine Prolonged Release Tablets Work
Mesalazine works locally on the inflamed intestinal mucosa. It inhibits the production of pro-inflammatory chemicals (such as prostaglandins and leukotrienes) and reduces the migration of white blood cells to the inflamed area. The prolonged-release formulation ensures that the drug is released slowly throughout the gastrointestinal tract, providing sustained anti-inflammatory action, especially in the colon.
Common Side Effects of Mesalazine Prolonged Release Tablets
While many people tolerate mesalazine well, some may experience side effects. Common ones include:
- Nausea or vomiting
- Diarrhea or abdominal discomfort
- Headache
- Flatulence
- Dizziness
Serious side effects are rare but may include kidney problems, blood disorders, or allergic reactions. If you notice unusual bruising, fever, rash, or changes in urination, seek medical help immediately.
Expert Advice for Mesalazine Prolonged Release Tablets
- Take this medicine exactly as prescribed by your doctor. Do not crush or chew the prolonged-release tablets; swallow them whole with water.
- Stay well hydrated while on this medication, as it may affect kidney function.
- Regular monitoring of kidney function and blood counts may be required, especially during long-term use.
- Inform your doctor if you have any pre-existing kidney or liver disease, or if you are pregnant or breastfeeding.
- Do not stop taking this medicine abruptly without consulting your doctor, as it may cause a relapse of symptoms.
Jan Aushadhi Price and Availability
Under the Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP), Mesalazine Prolonged Release Tablets IP 500mg are available at a highly subsidized price. The MRP for a strip of 10 tablets is ₹70.32, making it an affordable option for patients requiring long-term therapy. You can find this medicine at your nearest Jan Aushadhi Kendra. Always verify the composition and strength with the pharmacist.
Safety Note
This information is for educational purposes only and should not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medication. Do not self-medicate or switch brands without medical guidance. Ensure that the medicine you purchase has the correct generic composition and strength as prescribed.