Sitagliptin 50mg and Metformin 500mg Extended Release Tablets: Uses
This combination medicine is used to improve blood sugar control in adults with type 2 diabetes mellitus. It is prescribed when diet and exercise alone or with other diabetes medications do not provide adequate glycemic control. The extended-release formulation of metformin allows for once-daily dosing and may reduce gastrointestinal side effects.
How Sitagliptin and Metformin Extended Release works
Sitagliptin belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the levels of incretin hormones, which stimulate insulin release from the pancreas in response to meals and reduce the amount of glucose produced by the liver. Metformin is a biguanide that works by decreasing glucose production in the liver, decreasing absorption of glucose from the intestines, and improving insulin sensitivity. Together, they target multiple defects in type 2 diabetes.
Common side effects of Sitagliptin and Metformin Extended Release
- Nausea, vomiting, diarrhea, stomach upset
- Headache
- Upper respiratory tract infection
- Joint pain
- Low blood sugar (hypoglycemia) especially when used with other diabetes medications
- Metallic taste in mouth
Expert advice for Sitagliptin and Metformin Extended Release
- Take this medicine exactly as prescribed by your doctor. Do not crush or chew the extended-release tablets; swallow them whole.
- Monitor your blood sugar regularly as advised by your healthcare provider.
- Inform your doctor if you have kidney problems, liver disease, or a history of pancreatitis.
- Avoid alcohol while taking this medicine as it may increase the risk of lactic acidosis (a rare but serious side effect).
- If you experience symptoms of pancreatitis (severe abdominal pain, nausea, vomiting), seek medical attention immediately.
- This medicine is not recommended for use in type 1 diabetes or diabetic ketoacidosis.
Jan Aushadhi price and availability
The Jan Aushadhi price for Sitagliptin 50mg and Metformin 500mg Extended Release Tablets (10 tablets) is ₹51.57. This is significantly lower than many branded alternatives, making it an affordable option for diabetes management. You can purchase this medicine at any Jan Aushadhi Kendra across India. Always verify the composition and strength with your doctor or pharmacist before use.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medication. Do not self-medicate or change your dosage without medical supervision. The safety and efficacy of this medicine depend on individual health conditions and should be assessed by a healthcare professional.