Teneligliptin 20mg + Metformin Hydrochloride 1000mg (SR) + Pioglitazone 15mg Tablets: Uses, Benefits & Expert Advice
This triple combination tablet is prescribed for the management of type 2 diabetes mellitus in adults when diet, exercise, and single or dual therapy do not provide adequate glycemic control. It combines three different mechanisms to lower blood sugar levels effectively.
Uses of Teneligliptin + Metformin + Pioglitazone
- Improves glycemic control in type 2 diabetes
- Reduces fasting and post-meal blood glucose levels
- Helps lower HbA1c (glycated hemoglobin) over time
- May aid in weight management (metformin component)
- Supports insulin sensitivity (pioglitazone component)
How Teneligliptin + Metformin + Pioglitazone works
This combination works through three complementary actions: Teneligliptin is a DPP-4 inhibitor that increases incretin hormones, which stimulate insulin release and reduce glucagon secretion after meals. Metformin decreases glucose production by the liver and improves insulin sensitivity in muscles. Pioglitazone is a thiazolidinedione that reduces insulin resistance in fat and muscle tissues. Together, they provide comprehensive blood sugar control.
Common side effects of Teneligliptin + Metformin + Pioglitazone
- Hypoglycemia (low blood sugar) – especially if combined with other antidiabetic drugs
- Gastrointestinal issues: nausea, diarrhea, abdominal discomfort (common with metformin)
- Weight gain (pioglitazone may cause fluid retention)
- Headache, dizziness, or joint pain
- Upper respiratory tract infection
Expert advice for Teneligliptin + Metformin + Pioglitazone
- Take this medicine exactly as prescribed by your doctor, usually once or twice daily with meals to reduce stomach upset.
- Monitor your blood sugar regularly, especially when starting therapy or adjusting doses.
- Inform your doctor if you have a history of heart failure, liver disease, kidney problems, or bladder cancer (pioglitazone may increase risk).
- Avoid alcohol as it can increase the risk of lactic acidosis (rare but serious with metformin).
- Do not skip meals; maintain a consistent carbohydrate intake to prevent hypoglycemia.
- If you experience symptoms of hypoglycemia (sweating, shakiness, confusion), consume fast-acting sugar (glucose tablets, fruit juice) and follow up with a snack.
- This medicine is not for type 1 diabetes or diabetic ketoacidosis.
Jan Aushadhi price and availability
At Jan Aushadhi Kendras, this triple combination tablet (Teneligliptin 20mg + Metformin HCl 1000mg SR + Pioglitazone 15mg) is available at an affordable price of ₹70.32 for 10 tablets. This is significantly lower than branded alternatives, making diabetes management accessible. Always check the packaging for the correct composition and expiry date. You can find this medicine at your nearest Jan Aushadhi Kendra or order online through authorized platforms.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medication. Do not change your dose or stop taking this medicine without medical guidance. If you experience any severe side effects like shortness of breath, swelling in legs, or signs of lactic acidosis (muscle pain, weakness, stomach discomfort), seek immediate medical help.