Glipizide 5mg and Metformin Hydrochloride 500mg Tablets: Uses
This combination medicine is used to improve blood sugar control in adults with type 2 diabetes mellitus. It is typically prescribed when diet, exercise, and a single medication have not been enough to manage blood glucose levels. The two active ingredients work together to lower blood sugar in different ways.
How Glipizide and Metformin works
Glipizide belongs to a class of drugs called sulfonylureas. It stimulates the pancreas to release more insulin, especially after meals. Metformin is a biguanide that works by decreasing the amount of sugar produced by the liver and improving the body's sensitivity to insulin. Together, they provide a dual approach to controlling blood sugar levels.
Common side effects of Glipizide and Metformin
- Hypoglycemia (low blood sugar) – symptoms include sweating, dizziness, hunger, shakiness, and confusion
- Gastrointestinal issues – nausea, diarrhea, stomach upset, metallic taste
- Weight gain (more common with glipizide)
- Lactic acidosis (rare but serious – seek immediate medical help if you experience muscle pain, trouble breathing, unusual sleepiness)
Expert advice for Glipizide and Metformin
- Take this medicine exactly as prescribed by your doctor, usually once or twice daily with meals to reduce stomach upset.
- Monitor your blood sugar regularly, especially when starting treatment or changing doses.
- Never skip meals while on this medication, as it can increase the risk of hypoglycemia.
- Avoid alcohol – it can cause dangerous drops in blood sugar and increase the risk of lactic acidosis.
- Inform your doctor if you have kidney or liver problems, heart failure, or if you are going to have surgery or an imaging procedure that uses contrast dye.
- Do not stop this medication without consulting your doctor, as blood sugar may rise sharply.
Jan Aushadhi price and availability
Glipizide 5mg and Metformin Hydrochloride 500mg Tablets are available at Jan Aushadhi Kendras across India at an affordable price of ₹8.44 for a strip of 10 tablets. This makes it a cost-effective generic alternative to many branded versions. Always check the packaging for the Jan Aushadhi logo and verify the composition with your pharmacist.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or healthcare provider before starting or changing any medication. Do not use this medicine if you are allergic to glipizide, metformin, or any other ingredients. Keep out of reach of children.