Streptokinase Injection IP 15,00,000 IU Uses
Streptokinase Injection is a thrombolytic (clot-dissolving) medicine used in emergency settings to treat serious blood clots. It is primarily used for:
- Acute myocardial infarction (heart attack) – to dissolve clots blocking coronary arteries
- Pulmonary embolism – to break up clots in the lungs
- Deep vein thrombosis (DVT) – to treat clots in deep veins, usually in the legs
- Arterial thromboembolism – to restore blood flow in blocked arteries
- Clotted arteriovenous cannulae or shunts – to clear blocked dialysis access devices
How Streptokinase Injection Works
Streptokinase is a thrombolytic agent that works by activating the body's own fibrinolytic system. It binds to plasminogen, forming an activator complex that converts plasminogen to plasmin. Plasmin then breaks down fibrin, the main structural component of blood clots, thereby dissolving the clot and restoring blood flow through the affected vessel. This action is crucial in life-threatening conditions where rapid clot dissolution is needed.
Common Side Effects of Streptokinase Injection
- Bleeding (e.g., at injection sites, gums, nose, or internal bleeding)
- Allergic reactions (rash, itching, fever, anaphylaxis)
- Hypotension (low blood pressure)
- Nausea and vomiting
- Back pain
- Arrhythmias (irregular heartbeat) during heart attack treatment
Serious bleeding (e.g., intracranial hemorrhage) is a rare but critical risk. Patients should be monitored closely.
Expert Advice for Streptokinase Injection
- Streptokinase is administered only in a hospital setting under strict medical supervision, usually in an intensive care unit or emergency department.
- It is typically given as a single intravenous infusion over 30–60 minutes, with dose adjusted based on the condition.
- Because of the risk of bleeding, patients with recent surgery, trauma, stroke, or bleeding disorders may not be suitable candidates.
- Allergic reactions can occur; previous exposure to streptokinase (or streptococcal infection) may increase risk. An alternative thrombolytic may be considered if prior use is known.
- Blood pressure, heart rate, and signs of bleeding must be monitored throughout treatment.
- Do not use this medicine at home; it is for hospital use only.
Jan Aushadhi Price and Availability
Streptokinase Injection IP 15,00,000 IU is available at Jan Aushadhi Kendras across India at a highly affordable price of ₹932.82 per vial (10 ml with WFI). This is significantly lower than many branded alternatives, making life-saving thrombolytic therapy accessible to more patients. Always verify the batch and expiry date with the pharmacist.
Safety Note
This information is for educational purposes only and does not replace professional medical advice. Streptokinase is a potent medicine with serious risks, including major bleeding. It must be prescribed and administered by a qualified healthcare professional in a hospital setting. Do not self-administer or use without a doctor's supervision. Always consult your doctor or pharmacist for complete safety information.