Leflunomide Tablets IP 20mg Uses
Leflunomide is a disease-modifying antirheumatic drug (DMARD) used primarily to treat active rheumatoid arthritis in adults. It helps reduce joint pain, swelling, and stiffness, and can slow down the progression of joint damage. It is also sometimes used for psoriatic arthritis. This medicine is prescribed when other treatments have not worked well enough.
How Leflunomide works
Leflunomide works by blocking an enzyme called dihydroorotate dehydrogenase, which is involved in the production of pyrimidine nucleotides. This action reduces the proliferation of activated lymphocytes (a type of white blood cell) that contribute to the inflammatory process in rheumatoid arthritis. By suppressing the immune response, it decreases inflammation and joint destruction.
Common side effects of Leflunomide
- Diarrhea, nausea, vomiting
- Headache, dizziness
- Hair loss (usually mild and reversible)
- Skin rash or itching
- Elevated liver enzymes
- Increased blood pressure
- Respiratory infections
Expert advice for Leflunomide
- Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop without consulting your doctor.
- Regular blood tests (liver function, complete blood count, blood pressure) are necessary while on this medication.
- Leflunomide can cause liver damage. Avoid alcohol completely during treatment.
- It may take 4-6 weeks to see improvement and up to 6 months for full benefit. Be patient and consistent.
- Women of childbearing age must use effective contraception during treatment and for up to 2 years after stopping (due to long half-life). Men should also use contraception during and for 3 months after treatment.
- Do not take live vaccines while on Leflunomide.
- If you experience persistent diarrhea, unexplained weight loss, or yellowing of skin/eyes, inform your doctor immediately.
Jan Aushadhi price and availability
Leflunomide Tablets IP 20mg is available at Jan Aushadhi Kendras across India at an affordable price of ₹69.38 for a strip of 10 tablets. This generic version offers the same quality and effectiveness as branded alternatives but at a fraction of the cost. You can find it at your nearest Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP) outlet. Always check the batch and expiry before purchase.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medicine. Do not use Leflunomide if you are pregnant, planning to become pregnant, or breastfeeding. Inform your doctor about all other medicines you are taking, including over-the-counter drugs and supplements, to avoid interactions.