Terlipressin Injection 1000 mcg (1 mg/10ml) Uses
Terlipressin is a synthetic hormone used primarily in hospital settings for the management of acute esophageal variceal bleeding, a life-threatening complication of liver cirrhosis. It is also used in hepatorenal syndrome (type 1) to improve kidney function in patients with advanced liver disease. Additionally, it may be used in certain cases of septic shock as a vasopressor agent.
How Terlipressin works
Terlipressin is a prodrug that is converted in the body to lysine-vasopressin, which acts on V1 receptors in vascular smooth muscle. This causes potent vasoconstriction, particularly in the splanchnic circulation, reducing portal venous pressure and controlling bleeding from esophageal varices. In hepatorenal syndrome, it improves renal blood flow and glomerular filtration rate by increasing systemic vascular resistance and mean arterial pressure.
Common side effects of Terlipressin
- Abdominal cramps
- Pallor (pale skin)
- Increased blood pressure
- Bradycardia (slow heart rate)
- Diarrhea
- Nausea
- Headache
- Peripheral ischemia (rare)
Expert advice for Terlipressin
Terlipressin is a prescription-only medicine administered intravenously under strict medical supervision, typically in an intensive care or emergency setting. It should not be used in patients with uncontrolled hypertension, severe cardiac disease, or asthma. Continuous monitoring of blood pressure, heart rate, and oxygen saturation is essential during infusion. Do not self-administer or use without a doctor's prescription. Always verify the correct strength and dosage with your healthcare provider.
Jan Aushadhi price and availability
Terlipressin Injection 1000 mcg (1 mg/10ml) is available at Jan Aushadhi Kendras at an affordable price of ₹210.94 per 10 ml vial. This generic alternative offers significant cost savings compared to branded versions, making essential emergency treatment more accessible. Check with your nearest Jan Aushadhi Kendra for stock availability.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult a qualified doctor or pharmacist before using any medicine. Verify the composition, strength, and suitability of Terlipressin with your healthcare provider. Do not use this medicine without a valid prescription.