Apremilast Tablets IP 30mg: Uses
Apremilast is a prescription medicine used to treat certain inflammatory conditions. It is primarily used for:
- Psoriatic arthritis – to reduce joint pain, swelling, and stiffness in adults.
- Plaque psoriasis – to treat moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.
- Behçet’s disease – to treat oral ulcers associated with Behçet’s disease in adults.
Apremilast is not a cure but helps manage symptoms and improve quality of life. Always consult your doctor for the specific condition being treated.
How Apremilast works
Apremilast is a phosphodiesterase 4 (PDE4) inhibitor. It works by reducing the activity of an enzyme called PDE4, which is involved in the inflammatory process. By inhibiting PDE4, apremilast decreases the production of pro-inflammatory substances (like cytokines) and increases anti-inflammatory mediators. This helps to control inflammation, reduce skin plaques, and relieve joint symptoms in conditions like psoriasis and psoriatic arthritis.
Common side effects of Apremilast
Like all medicines, apremilast can cause side effects, although not everyone gets them. Common side effects include:
- Diarrhea
- Nausea
- Headache
- Upper respiratory tract infection
- Abdominal pain
- Vomiting
- Fatigue
- Insomnia
- Decreased appetite
- Weight loss
Most side effects are mild to moderate and may improve over time. However, if diarrhea or nausea becomes severe, or if you notice signs of depression, mood changes, or suicidal thoughts, contact your doctor immediately.
Expert advice for Apremilast
- Take as prescribed: Apremilast is usually taken twice daily, with or without food. Follow your doctor’s dosing instructions carefully.
- Dose titration: To reduce gastrointestinal side effects, your doctor may start with a lower dose and gradually increase it over the first week.
- Monitor weight: Apremilast can cause weight loss. Your doctor may check your weight regularly.
- Mood changes: Inform your doctor if you have a history of depression or suicidal thoughts. Apremilast may increase the risk of mood changes.
- Avoid pregnancy: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks with your doctor.
- Kidney function: If you have severe kidney problems, your doctor may adjust your dose.
- Vaccinations: Avoid live vaccines while taking apremilast. Discuss any needed vaccinations with your doctor.
Jan Aushadhi price and availability
Apremilast Tablets IP 30mg are available at Jan Aushadhi Kendras under the Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP). The Jan Aushadhi price for a strip of 10 tablets is ₹129.38, which is significantly lower than many branded alternatives. This makes treatment more affordable for patients with chronic conditions like psoriasis and psoriatic arthritis. Always check the packaging for the correct composition and strength. Availability may vary by location; you can inquire at your nearest Jan Aushadhi Kendra.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult a qualified doctor or pharmacist before starting any new medicine. Do not self-medicate or change your dose without medical supervision. Verify the composition, strength, and suitability of Apremilast Tablets IP 30mg with your healthcare provider. Report any serious side effects to your doctor immediately.