Doxorubicin Injection IP 50mg (2mg per ml) Uses
Doxorubicin is a chemotherapy medication used to treat various types of cancer, including breast cancer, bladder cancer, lymphoma, leukemia, and many others. It is often part of a combination chemotherapy regimen. The injection is given intravenously (into a vein) under the supervision of a qualified healthcare professional.
How Doxorubicin works
Doxorubicin belongs to a class of drugs called anthracyclines. It works by interfering with the growth and multiplication of cancer cells. Specifically, it inhibits an enzyme called topoisomerase II, which is essential for DNA replication, and it also intercalates (inserts itself) between DNA base pairs, preventing the DNA from being copied properly. This leads to cell death, particularly in rapidly dividing cancer cells.
Common side effects of Doxorubicin
- Nausea and vomiting
- Hair loss (alopecia)
- Low blood cell counts (anemia, neutropenia, thrombocytopenia) leading to increased risk of infection, fatigue, and bleeding
- Mouth sores (mucositis)
- Red discoloration of urine (harmless but may be alarming)
- Heart damage (cardiotoxicity) – a serious side effect that may occur with higher cumulative doses
- Skin reactions at the injection site (redness, pain, or tissue damage if the drug leaks out of the vein)
Expert advice for Doxorubicin
- Doxorubicin should only be administered by experienced oncology healthcare providers in a hospital or clinic setting.
- Your doctor will monitor your heart function before and during treatment, as doxorubicin can cause cumulative heart damage.
- Regular blood tests are necessary to check your blood cell counts and organ function.
- Inform your doctor about all other medicines you are taking, as doxorubicin can interact with many drugs.
- Do not receive live vaccines during treatment without consulting your doctor.
- Use effective contraception during treatment and for some time after, as doxorubicin can harm an unborn baby.
- Report any signs of infection (fever, sore throat), unusual bleeding, or shortness of breath to your doctor immediately.
Jan Aushadhi price and availability
Doxorubicin Injection IP 50mg (2mg per ml) is available at Jan Aushadhi Kendras at a highly affordable price of ₹281.25 per vial. This generic version offers the same quality and effectiveness as branded alternatives but at a fraction of the cost. Availability may vary by location; check with your nearest Jan Aushadhi Kendra or the official PMBJP website for stock details.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Doxorubicin is a potent chemotherapy drug with serious potential side effects. Always consult your oncologist or healthcare provider for personalized guidance regarding your treatment plan, dosage, and monitoring. Do not self-administer or change your medication without medical supervision.