Trimetazidine Hydrochloride Controlled Release Capsules 60mg Uses
Trimetazidine Hydrochloride Controlled Release Capsules 60mg is primarily used in the management of angina pectoris (chest pain due to reduced blood flow to the heart). It is often prescribed as an add-on therapy for patients who are not adequately controlled by other anti-anginal medications. This medicine helps improve exercise tolerance and reduces the frequency of angina attacks. It is also used for the symptomatic treatment of vertigo and tinnitus (ringing in the ears) in some cases, though its primary approved use in India is for angina.
How Trimetazidine Hydrochloride Controlled Release Capsules 60mg works
Trimetazidine works by a unique mechanism that is different from other anti-anginal drugs. It inhibits the enzyme 3-ketoacyl coenzyme A thiolase (3-KAT), which shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation. This metabolic switch improves the efficiency of oxygen use by the heart muscle, thereby protecting it from ischemia (lack of oxygen). By optimizing energy production, trimetazidine helps maintain cellular function during low-oxygen conditions, reducing the frequency of angina episodes and improving exercise capacity.
Common side effects of Trimetazidine Hydrochloride Controlled Release Capsules 60mg
Like all medicines, this medication can cause side effects, although not everyone gets them. Common side effects may include:
- Dizziness or headache
- Gastrointestinal disturbances such as nausea, vomiting, or diarrhea
- Fatigue or weakness
- Palpitations (feeling of rapid or irregular heartbeat)
- Skin rash or itching
If any of these side effects persist or worsen, inform your doctor promptly. Serious side effects are rare but may include symptoms of Parkinson's disease (tremor, rigidity) or other movement disorders, especially in elderly patients. Seek immediate medical attention if you experience any severe reactions.
Expert advice for Trimetazidine Hydrochloride Controlled Release Capsules 60mg
- Take this medicine exactly as prescribed by your doctor. Do not alter the dose or stop taking it without consulting your doctor.
- This is a controlled-release capsule; swallow it whole with water. Do not crush, chew, or open the capsule, as it is designed to release the medicine slowly.
- Inform your doctor about all other medicines you are taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid potential interactions.
- If you have a history of Parkinson's disease, tremors, or other movement disorders, discuss this with your doctor before starting trimetazidine.
- Regular monitoring by your doctor is important to assess the effectiveness of the treatment and to check for any side effects.
- Avoid sudden discontinuation of this medicine, as it may worsen your condition.
Jan Aushadhi price and availability
Trimetazidine Hydrochloride Controlled Release Capsules 60mg is available at Jan Aushadhi Kendra (Pradhan Mantri Bhartiya Janaushadhi Pariyojana) stores across India at an affordable price. The MRP for a strip of 10 capsules is ₹41.25, making it a cost-effective generic alternative to expensive branded versions. This initiative by the Government of India aims to provide quality generic medicines at low prices, ensuring that patients have access to essential treatments without financial burden. You can find this medicine at your nearest Jan Aushadhi store; check the official PMBJP website for store locations.
Safety note
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before starting any new medication. Do not use this medicine without a prescription. Verify the composition, strength, and suitability of this medicine with your healthcare provider. If you experience any unusual symptoms or side effects, seek medical attention immediately. Keep this medicine out of reach of children and store it as directed.