Agomelatine Tablets 25 mg Uses
Agomelatine is a medicine primarily used in the treatment of major depressive disorder (MDD) in adults. It helps to relieve the symptoms of depression, such as low mood, loss of interest, feelings of worthlessness, and disturbed sleep. It is often considered when other antidepressants have not been effective or have caused unwanted side effects.
How Agomelatine Tablets 25 mg Works
Agomelatine works by acting on two systems in the brain. It is a melatonin receptor agonist, meaning it mimics the action of melatonin, a hormone that regulates the body's sleep-wake cycle. This helps to improve sleep quality and resynchronize the circadian rhythm. Additionally, it acts as a serotonin receptor antagonist (specifically 5-HT2C), which leads to an increase in the release of dopamine and norepinephrine in certain brain areas, helping to improve mood and reduce depressive symptoms.
Common Side Effects of Agomelatine Tablets 25 mg
Like all medicines, agomelatine can cause side effects, although not everyone gets them. Common side effects (may affect up to 1 in 10 people) include:
- Headache
- Dizziness
- Drowsiness or fatigue
- Nausea or diarrhea
- Constipation
- Anxiety or agitation
- Back pain
- Increased sweating
Some side effects may require medical attention. If you experience signs of liver problems (such as yellowing of the skin or eyes, dark urine, or unexplained itching), stop the medicine and consult your doctor immediately.
Expert Advice for Agomelatine Tablets 25 mg
- Take agomelatine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor.
- It is usually taken once daily at bedtime, as it can help with sleep.
- Your doctor may perform liver function tests before starting treatment and periodically during treatment to monitor for any liver issues.
- Avoid alcohol while taking this medicine, as it may increase the risk of liver damage.
- Inform your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, to avoid interactions.
- Agomelatine may cause drowsiness or dizziness; do not drive or operate machinery until you know how it affects you.
- Do not use agomelatine during pregnancy or breastfeeding unless clearly advised by your doctor.
Jan Aushadhi Price and Availability
Agomelatine Tablets 25 mg is available at Jan Aushadhi Kendra under the Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP). The MRP for a strip of 10 tablets is ₹61.88, making it an affordable generic alternative to more expensive branded versions. You can find it at your nearest Jan Aushadhi store. Always check the packaging for the 'Jan Aushadhi' logo and verify the composition with your pharmacist.
Safety Note
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before starting any new medicine. Do not self-medicate. Ensure that the medicine you purchase has the correct generic name and strength as prescribed. If you experience any severe or persistent side effects, seek medical help immediately.