Alprazolam 0.5mg and Sertraline Hydrochloride 25mg Tablets

Product Details

  • Unit Size 10's
  • Jan Aushadhi MRP ₹23.44
  • Last Updated August 11, 2026
  • Data Source PMBJP Official Drug Database

Alprazolam 0.5mg and Sertraline Hydrochloride 25mg Tablets: Uses

This combination medicine is primarily used in the management of anxiety disorders, panic attacks, and depression with associated anxiety. It is often prescribed when a patient needs rapid relief from acute anxiety symptoms while the antidepressant effect of sertraline builds up over time. The combination helps in stabilizing mood and reducing excessive worry, fear, and tension.

How Alprazolam 0.5mg and Sertraline Hydrochloride 25mg Tablets work

Alprazolam belongs to a class of medicines called benzodiazepines. It works by enhancing the effect of a natural chemical in the brain called gamma-aminobutyric acid (GABA), which produces a calming effect and reduces abnormal excitement in the brain. Sertraline is a selective serotonin reuptake inhibitor (SSRI). It increases the level of serotonin, a neurotransmitter that helps regulate mood, sleep, and appetite. Together, they provide a dual action: alprazolam offers quick relief from anxiety symptoms, while sertraline works over a few weeks to correct the underlying chemical imbalance associated with depression and anxiety disorders.

Common side effects of Alprazolam 0.5mg and Sertraline Hydrochloride 25mg Tablets

Like all medicines, this combination can cause side effects, although not everyone gets them. Common side effects may include:

  • Drowsiness, dizziness, or lightheadedness
  • Fatigue or weakness
  • Dry mouth
  • Nausea, loss of appetite, or diarrhea
  • Increased sweating
  • Sleep disturbances (insomnia or vivid dreams)
  • Changes in libido or sexual function
  • Blurred vision or difficulty concentrating

These side effects are usually mild and may subside as your body adjusts to the medicine. However, if any side effect persists or worsens, inform your doctor.

Expert advice for Alprazolam 0.5mg and Sertraline Hydrochloride 25mg Tablets

  • Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice, as sudden withdrawal can cause severe symptoms.
  • Alprazolam can be habit-forming. Use it only for the duration prescribed by your doctor.
  • Avoid alcohol while taking this medicine, as it can increase drowsiness and the risk of side effects.
  • Do not drive or operate heavy machinery until you know how this medicine affects you, as it may cause drowsiness or dizziness.
  • Inform your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, to avoid interactions.
  • It may take 2 to 4 weeks for sertraline to show its full therapeutic effect. Do not get discouraged if you do not feel better immediately.
  • If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine.
  • Do not crush or chew the tablets; swallow them whole with water.

Jan Aushadhi price and availability

This medicine is available at Jan Aushadhi Kendra stores across India under the Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP). The MRP for a strip of 10 tablets is ₹23.44, which is significantly lower than most branded alternatives. You can purchase it from any authorized Jan Aushadhi store. To find the nearest store, visit the official Jan Aushadhi website or ask at your local pharmacy.

Safety note

This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before starting any new medicine. Do not self-medicate or change your dosage without medical supervision. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight.

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Known Brand Alternatives

This Jan Aushadhi medicine is a generic equivalent for:

Anxit Plus Alprax Plus Serenex Plus Zolam Plus Sertralin Plus

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Frequently Asked Questions

What is the Jan Aushadhi price for Alprazolam 0.5mg and Sertraline 25mg tablets?

The MRP for a strip of 10 tablets is ₹23.44 at Jan Aushadhi Kendra stores. This is much cheaper than branded versions.

Can I take Alprazolam and Sertraline together?

Yes, this combination is prescribed for certain conditions like anxiety with depression. However, it should only be taken under a doctor's supervision, as both medicines have potential for dependence and side effects.

How long does it take for this medicine to work?

Alprazolam starts working within 30-60 minutes for anxiety relief, but sertraline may take 2-4 weeks to show its full antidepressant effect. Follow your doctor's guidance.

Is it safe to stop taking this medicine suddenly?

No, sudden withdrawal can cause severe symptoms like rebound anxiety, insomnia, and seizures. Always taper the dose under medical supervision.

Disclaimer: Information is for educational and reference purposes only. Always consult a qualified doctor or pharmacist before changing medicines. Do not replace prescribed medicines without medical advice.

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