Dapagliflozin 5mg and Metformin Hydrochloride (Extended Release) 500mg Tablets: Uses
This combination medicine is used to improve blood sugar control in adults with type 2 diabetes mellitus. It is typically prescribed when diet, exercise, and a single medication (like metformin alone) have not provided adequate glycemic control. The two active ingredients work together to lower blood glucose levels in different ways.
How Dapagliflozin + Metformin ER works
Dapagliflozin belongs to a class of drugs called SGLT2 inhibitors. It works by blocking the reabsorption of glucose in the kidneys, causing excess sugar to be excreted in the urine. Metformin (extended release) works primarily by decreasing the amount of glucose produced by the liver and improving the body's sensitivity to insulin, helping muscles use glucose more effectively. The extended-release formulation allows for once-daily dosing and may cause fewer gastrointestinal side effects compared to immediate-release metformin.
Common side effects of Dapagliflozin + Metformin ER
- Urinary tract infections (UTIs) and genital yeast infections (due to increased sugar in urine)
- Nausea, diarrhea, or stomach upset (especially when starting metformin)
- Dehydration or dizziness (due to increased urination from dapagliflozin)
- Low blood sugar (hypoglycemia) when used with other diabetes medications like insulin or sulfonylureas
- Rare but serious: lactic acidosis (metformin) and ketoacidosis (dapagliflozin) – seek immediate medical help if symptoms like unusual tiredness, muscle pain, or difficulty breathing occur
Expert advice for Dapagliflozin + Metformin ER
- Take this medicine exactly as prescribed, usually once daily with a meal to reduce stomach upset.
- Stay well hydrated to reduce the risk of dehydration and kidney problems.
- Monitor your blood sugar regularly, especially when starting treatment or adjusting doses.
- Avoid alcohol while taking metformin to reduce the risk of lactic acidosis.
- Inform your doctor if you have a history of kidney disease, liver disease, or heart failure.
- Do not use if you have type 1 diabetes or diabetic ketoacidosis.
- If you experience symptoms of a urinary tract infection (painful urination, fever, back pain) or genital infection (itching, redness, discharge), consult your doctor promptly.
Jan Aushadhi price and availability
Under the Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP), Dapagliflozin 5mg + Metformin Hydrochloride ER 500mg tablets are available at a highly affordable price of ₹28.13 for a strip of 10 tablets. This is significantly lower than many branded alternatives, making diabetes management more accessible. You can find this medicine at any Jan Aushadhi Kendra across India. Always check the packaging for the Jan Aushadhi logo and verify the composition with your pharmacist.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medication. Do not change your dose or stop taking this medicine without medical guidance. If you experience any severe side effects or signs of an allergic reaction (rash, swelling, difficulty breathing), seek emergency medical help immediately.