Dapagliflozin 10mg, Vildagliptin 100mg (SR) and Metformin Hydrochloride 500mg (SR) Tablets Uses
This triple combination tablet is used to improve blood sugar control in adults with type 2 diabetes mellitus. It is typically prescribed when diet, exercise, and single or dual therapy do not provide adequate glycemic control. The combination helps reduce blood glucose levels through complementary mechanisms.
How Dapagliflozin + Vildagliptin + Metformin works
This medicine contains three active ingredients that work together to control blood sugar:
- Dapagliflozin (10mg): Belongs to the SGLT2 inhibitor class. It blocks glucose reabsorption in the kidneys, causing excess sugar to be excreted in urine.
- Vildagliptin (100mg SR): A DPP-4 inhibitor that increases levels of incretin hormones, which stimulate insulin release after meals and reduce glucagon secretion.
- Metformin (500mg SR): The first-line diabetes drug that decreases glucose production in the liver, improves insulin sensitivity, and reduces sugar absorption in the intestines.
The sustained-release (SR) formulations of vildagliptin and metformin provide prolonged action, allowing once-daily dosing in many cases.
Common side effects of Dapagliflozin + Vildagliptin + Metformin
Like all medicines, this combination may cause side effects. Common ones include:
- Urinary tract infections and genital fungal infections (due to dapagliflozin)
- Nausea, diarrhea, or stomach upset (especially when starting metformin)
- Headache, dizziness, or weakness
- Nasopharyngitis (common cold symptoms)
- Hypoglycemia (low blood sugar) when used with other diabetes medications like insulin or sulfonylureas
Serious side effects are rare but may include pancreatitis, lactic acidosis (very rare with metformin), severe allergic reactions, or kidney problems. Seek immediate medical help if you experience symptoms like persistent nausea, vomiting, abdominal pain, or difficulty breathing.
Expert advice for Dapagliflozin + Vildagliptin + Metformin
- Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop without consulting your healthcare provider.
- This combination is usually taken once or twice daily with meals to reduce stomach upset. Follow your doctor's instructions.
- Monitor your blood sugar regularly as advised. Keep a log to share with your doctor.
- Stay well hydrated, especially if you experience vomiting or diarrhea, as dapagliflozin can increase dehydration risk.
- Inform your doctor about all other medicines you take, including over-the-counter drugs and supplements, to avoid interactions.
- If you have kidney disease, liver problems, or a history of pancreatitis, discuss with your doctor before starting this medicine.
- Do not consume alcohol excessively, as it can increase the risk of lactic acidosis with metformin.
- If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine.
Jan Aushadhi price and availability
This Jan Aushadhi product (Dapagliflozin 10mg + Vildagliptin 100mg SR + Metformin 500mg SR) is available at a highly affordable price of ₹60.94 for a strip of 15 tablets. This is significantly cheaper than branded alternatives, making diabetes management more accessible. You can purchase it from any Jan Aushadhi Kendra across India. Always check the packaging for the correct composition and expiry date.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medicine. Verify the composition, strength, and suitability of this product with your healthcare provider. Do not self-medicate or share your medicine with others.