Gliclazide + Pioglitazone + Metformin Tablet (30/15/500 mg) Uses
This combination medicine is used to improve blood sugar control in adults with type 2 diabetes mellitus when diet, exercise, and single-agent therapy do not provide adequate glycemic control. It is typically prescribed for patients who need multiple mechanisms of action to manage their blood glucose levels.
How Gliclazide + Pioglitazone + Metformin works
This triple combination works through three complementary mechanisms:
- Gliclazide (a sulfonylurea) stimulates the pancreas to release more insulin.
- Pioglitazone (a thiazolidinedione) improves insulin sensitivity in muscle and fat tissues and reduces glucose production in the liver.
- Metformin (a biguanide) decreases glucose production in the liver, reduces absorption of glucose from the intestines, and improves insulin sensitivity.
Common side effects of Gliclazide + Pioglitazone + Metformin
Some common side effects include:
- Hypoglycemia (low blood sugar) – especially if meals are skipped or delayed
- Gastrointestinal issues like nausea, vomiting, diarrhea, or stomach upset
- Weight gain
- Edema (fluid retention) – more common with pioglitazone
- Headache or dizziness
Expert advice for Gliclazide + Pioglitazone + Metformin
Before starting this medicine, inform your doctor if you have a history of heart failure, liver disease, kidney problems, or bladder cancer. Pioglitazone may increase the risk of fluid retention and heart failure, especially in patients with pre-existing heart conditions. Regular monitoring of blood sugar, liver function, and kidney function is recommended. Avoid alcohol as it can increase the risk of lactic acidosis (a rare but serious side effect of metformin). This medicine should be taken with meals to reduce gastrointestinal discomfort. Do not stop or change your dose without consulting your doctor.
Jan Aushadhi price and availability
Gliclazide + Pioglitazone + Metformin Tablet (30/15/500 mg) is available at Jan Aushadhi Kendras across India at an affordable price. The MRP is price pending per strip of 10 tablets (price may vary slightly by location). This generic version offers the same quality and effectiveness as branded alternatives but at a fraction of the cost. You can check availability at your nearest Jan Aushadhi Kendra or online through the PMBJP portal.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medication. Verify the composition, strength, and suitability of this medicine with your healthcare provider. Do not use this medicine if you are allergic to any of its ingredients or if you have conditions like type 1 diabetes, diabetic ketoacidosis, or severe kidney/liver impairment.