Sitagliptin + Pioglitazone + Metformin Tablet (100/15/500 mg) Uses
This combination medicine is used for the management of type 2 diabetes mellitus when diet, exercise, and single or dual therapy do not provide adequate blood sugar control. It helps improve glycemic control by targeting multiple defects in type 2 diabetes.
How Sitagliptin + Pioglitazone + Metformin works
This triple combination works through three different mechanisms: Sitagliptin increases incretin hormones, which stimulate insulin release and reduce glucagon secretion; Pioglitazone improves insulin sensitivity in muscle and fat tissues; and Metformin decreases glucose production in the liver and improves insulin sensitivity. Together, they provide comprehensive blood sugar control.
Common side effects of Sitagliptin + Pioglitazone + Metformin
- Upper respiratory tract infection
- Headache
- Nausea, diarrhea, or stomach upset
- Weight gain (more likely with pioglitazone)
- Swelling in legs or ankles (edema)
- Low blood sugar (hypoglycemia) when used with other antidiabetic drugs
Expert advice for Sitagliptin + Pioglitazone + Metformin
- Take this medicine exactly as prescribed by your doctor, usually once or twice daily with meals to reduce stomach upset.
- Monitor your blood sugar regularly as advised by your doctor.
- Inform your doctor if you have a history of heart failure, liver disease, kidney problems, or bladder cancer.
- Avoid alcohol as it may increase the risk of lactic acidosis (especially with metformin).
- Do not stop this medicine without consulting your doctor, as blood sugar may rise.
- If you experience symptoms of low blood sugar (sweating, dizziness, confusion), consume glucose or sugar immediately.
Jan Aushadhi price and availability
This medicine is available at Jan Aushadhi Kendras across India at an affordable price. The MRP for a strip of 10 tablets is price pending (as per the product listing). However, please check with your local Jan Aushadhi Kendra for the current price and availability. The generic version offers significant cost savings compared to branded alternatives.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medicine. Verify the composition, strength, and suitability of this medicine with a healthcare professional. Do not use this medicine if you are allergic to any of its ingredients, or if you have severe kidney or liver disease, heart failure, or a history of diabetic ketoacidosis.