Chloroquine Phosphate Tablets IP 250 mg Uses
Chloroquine Phosphate is primarily used for the prevention and treatment of malaria caused by Plasmodium vivax, P. ovale, and P. malariae, as well as sensitive strains of P. falciparum. It is also used in the management of amebiasis (liver abscess) and certain autoimmune disorders like rheumatoid arthritis and lupus erythematosus (off-label).
How Chloroquine Phosphate works
Chloroquine is an antimalarial agent that works by interfering with the parasite's ability to break down hemoglobin. It accumulates in the parasite's food vacuole, raising the pH and inhibiting heme polymerization, which leads to toxic heme accumulation and parasite death. In autoimmune conditions, it modulates the immune response by suppressing T-cell activity and reducing inflammation.
Common side effects of Chloroquine Phosphate
- Nausea, vomiting, diarrhea
- Headache, dizziness
- Blurred vision (reversible upon discontinuation)
- Skin rash, itching
- Hair loss (rare)
- Mood changes or irritability
Expert advice for Chloroquine Phosphate
- Take Chloroquine exactly as prescribed; do not skip doses to ensure effective malaria prevention or treatment.
- Use with caution in patients with liver or kidney disease, as dose adjustment may be needed.
- Regular eye examinations are recommended during long-term therapy due to risk of retinal toxicity.
- Avoid alcohol as it may increase the risk of liver damage.
- Inform your doctor if you have a history of epilepsy, psoriasis, or G6PD deficiency.
Jan Aushadhi price and availability
Chloroquine Phosphate Tablets IP 250 mg are available at Jan Aushadhi Kendras across India at an affordable price of ₹5.00 for a strip of 10 tablets. This generic alternative offers significant cost savings compared to branded versions, making malaria treatment accessible to all.
Safety note
This content is for educational purposes only and does not replace professional medical advice. Always consult a qualified doctor or pharmacist before starting any medication. Verify the composition, strength, and suitability of Chloroquine Phosphate with your healthcare provider.