Drug Code: 472 Gastrointestinal (GIT)

Esomeprazole 40mg (Enteric-Coated) and Domperidone 30mg (Sustained Release) Capsules

Product Details

  • Unit Size 10's
  • Jan Aushadhi MRP ₹20.63
  • Last Updated June 1, 2026
  • Data Source PMBJP Official Drug Database

Esomeprazole 40mg + Domperidone 30mg Capsules: Uses, Benefits & Jan Aushadhi Price

This combination capsule contains Esomeprazole (40mg enteric-coated) and Domperidone (30mg sustained release). It is commonly prescribed for managing gastroesophageal reflux disease (GERD) with associated nausea, vomiting, or delayed gastric emptying. The enteric coating protects Esomeprazole from stomach acid, while the sustained release of Domperidone ensures prolonged effect.

Uses of Esomeprazole + Domperidone Capsules

  • Heartburn and acid reflux (GERD) when accompanied by nausea or vomiting
  • Gastroparesis (delayed stomach emptying) causing bloating, fullness, and nausea
  • Functional dyspepsia with reflux symptoms
  • Prevention of nausea and vomiting due to certain medications or conditions

How Esomeprazole + Domperidone Works

Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production by blocking the proton pumps in the stomach lining. Domperidone is a prokinetic agent that increases the movement of the stomach and intestines, helping food move more quickly through the digestive tract and reducing nausea. Together, they address both acid-related symptoms and motility issues.

Common Side Effects of Esomeprazole + Domperidone

  • Headache, dizziness
  • Dry mouth, diarrhea or constipation
  • Abdominal pain, flatulence
  • Rarely: skin rash, drowsiness, or extrapyramidal symptoms (involuntary movements) – seek medical help if these occur

Expert Advice for Esomeprazole + Domperidone Capsules

  • Take this medicine exactly as prescribed, usually before meals (Esomeprazole works best on an empty stomach).
  • Swallow the capsule whole; do not crush or chew the enteric-coated or sustained-release pellets.
  • Avoid alcohol and spicy/fatty foods to reduce stomach irritation.
  • Inform your doctor if you have liver disease, kidney problems, or a history of heart rhythm disorders (QT prolongation).
  • Long-term use of PPIs may increase risk of vitamin B12 deficiency, bone fractures, or kidney issues; use the lowest effective dose for the shortest duration.
  • Domperidone may cause drowsiness; avoid driving or operating machinery if affected.

Jan Aushadhi Price and Availability

The Jan Aushadhi generic version of Esomeprazole 40mg + Domperidone 30mg capsules is available at a highly affordable price of ₹20.63 for a strip of 10 capsules. This is significantly cheaper than many branded alternatives, making it an excellent option for patients seeking cost-effective treatment for GERD and nausea. You can find this medicine at any Jan Aushadhi Kendra across India. Always verify the composition and strength with your doctor or pharmacist before use.

Safety Note

This information is for educational purposes only and does not replace professional medical advice. Do not self-medicate. Always consult a qualified healthcare provider before starting any new medication, especially if you are pregnant, breastfeeding, or have underlying health conditions. Keep medicines out of reach of children.

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Known Brand Alternatives

This Jan Aushadhi medicine is a generic equivalent for:

Nexpro RD 40 Razid D 30 Esomac D 30 Esoz D 30 Sompraz D 30

Suggested Related Medicines

Frequently Asked Questions

What is the Jan Aushadhi price of Esomeprazole 40mg + Domperidone 30mg capsules?

The Jan Aushadhi price for a strip of 10 capsules is ₹20.63, which is much cheaper than most branded versions.

Can I take Esomeprazole + Domperidone capsules for long-term?

Long-term use should be under medical supervision. Prolonged use of PPIs may increase risk of vitamin B12 deficiency, bone fractures, or kidney issues. Domperidone is not recommended for long-term use due to potential heart rhythm effects.

How should I take Esomeprazole + Domperidone capsules?

Take the capsule whole, preferably before meals. Do not crush or chew the enteric-coated or sustained-release pellets. Follow your doctor's dosing schedule.

What are the common side effects of this Jan Aushadhi medicine?

Common side effects include headache, dry mouth, diarrhea, constipation, and abdominal pain. Rare but serious side effects like involuntary movements or irregular heartbeat require immediate medical attention.

Disclaimer: Information is for educational and reference purposes only. Always consult a qualified doctor or pharmacist before changing medicines. Do not replace prescribed medicines without medical advice.

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