Paracetamol 325mg and Tramadol 37.5mg Tablets: Uses, How It Works, Side Effects, and Expert Advice
This combination medicine contains two active ingredients: Paracetamol (325mg) and Tramadol (37.5mg). It is a prescription-only analgesic used for the management of moderate to moderately severe pain. Below is patient-friendly information to help you understand this medicine better.
Paracetamol 325mg and Tramadol 37.5mg Tablets Uses
This combination is used for short-term relief of moderate to moderately severe pain, such as:
- Post-surgical pain
- Dental pain
- Musculoskeletal pain (e.g., back pain, arthritis flare-ups)
- Pain from injuries or fractures
It is not intended for mild pain or long-term use. Always follow your doctor's advice regarding the duration of treatment.
How Paracetamol 325mg and Tramadol 37.5mg Tablets Work
Paracetamol is an analgesic and antipyretic that works by inhibiting the production of prostaglandins in the brain, which helps reduce pain and fever. Tramadol is a centrally acting opioid analgesic that binds to mu-opioid receptors and also inhibits the reuptake of serotonin and norepinephrine, enhancing pain relief. Together, they provide a synergistic effect for better pain control.
Common Side Effects of Paracetamol 325mg and Tramadol 37.5mg Tablets
Like all medicines, this combination can cause side effects, though not everyone gets them. Common side effects include:
- Nausea, vomiting, or constipation
- Dizziness, drowsiness, or headache
- Dry mouth or sweating
- Fatigue or weakness
Serious side effects are rare but may include allergic reactions, breathing problems, or seizures. Seek immediate medical help if you experience difficulty breathing, swelling of the face or throat, or severe skin reactions.
Expert Advice for Paracetamol 325mg and Tramadol 37.5mg Tablets
- Take this medicine exactly as prescribed. Do not exceed the recommended dose or duration.
- Avoid alcohol while taking this medicine, as it increases the risk of liver damage and central nervous system depression.
- Do not drive or operate heavy machinery if you feel dizzy or drowsy.
- Inform your doctor if you have a history of liver or kidney disease, seizures, head injury, or addiction to opioids.
- This medicine may cause dependence with long-term use. Use only for the shortest duration necessary.
- Do not take this medicine with other products containing paracetamol or tramadol to avoid overdose.
Jan Aushadhi Price and Availability
Under the Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP), Paracetamol 325mg + Tramadol 37.5mg tablets are available at a highly affordable price. The MRP for a strip of 10 tablets is ₹12.38, making it a cost-effective generic alternative to expensive branded versions. You can purchase this medicine at any Jan Aushadhi Kendra across India. Always verify the composition and strength with your doctor or pharmacist before use.
Safety Note
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor or pharmacist before starting any new medicine. Do not self-medicate or share this medicine with others. Keep out of reach of children. In case of overdose, seek emergency medical help immediately.