Cefotaxime Sodium 500mg and Sulbactam Sodium 250mg Injection: Uses, How It Works, Side Effects, and Jan Aushadhi Price
This combination injection contains Cefotaxime (a third-generation cephalosporin antibiotic) and Sulbactam (a beta-lactamase inhibitor). It is used to treat moderate to severe bacterial infections, including respiratory tract infections, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, septicemia, and meningitis. The addition of Sulbactam helps overcome bacterial resistance by inhibiting beta-lactamase enzymes that would otherwise destroy Cefotaxime.
How Cefotaxime + Sulbactam Injection works
Cefotaxime works by interfering with bacterial cell wall synthesis, leading to bacterial cell death. Sulbactam protects Cefotaxime from being broken down by resistant bacteria, thereby extending its spectrum of activity. This combination is effective against many Gram-positive and Gram-negative bacteria, including some strains that are resistant to Cefotaxime alone.
Common side effects of Cefotaxime + Sulbactam Injection
- Pain, redness, or swelling at the injection site
- Diarrhea, nausea, or vomiting
- Skin rash or itching
- Headache or dizziness
- Phlebitis (inflammation of the vein)
- Allergic reactions (rare but serious: difficulty breathing, swelling of face/lips/tongue)
Expert advice for Cefotaxime + Sulbactam Injection
- This medicine is given as an intramuscular or intravenous injection by a healthcare professional. Do not self-administer.
- Complete the full course of treatment as prescribed, even if you feel better, to prevent antibiotic resistance.
- Inform your doctor if you have a history of allergy to cephalosporins, penicillins, or other beta-lactam antibiotics.
- Use with caution in patients with kidney disease; dose adjustment may be needed.
- Monitor for signs of superinfection (e.g., oral thrush, vaginal yeast infection) during prolonged use.
- Avoid alcohol consumption during treatment and for at least 48 hours after the last dose to prevent disulfiram-like reactions.
Jan Aushadhi price and availability
The Jan Aushadhi price for Cefotaxime Sodium 500mg and Sulbactam Sodium 250mg Injection is ₹17.82 per vial with water for injection (Wfi). This is significantly lower than many branded alternatives, making it an affordable option for patients. It is available at Jan Aushadhi Kendras across India. Always check the batch and expiry before purchase.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Always consult a qualified doctor or pharmacist before using this medicine. Do not use this injection if you are allergic to any of its components. Keep out of reach of children. Report any severe or persistent side effects to your healthcare provider immediately.