Primaquine Phosphate Tablets IP 7.5 mg Uses
Primaquine Phosphate Tablets IP 7.5 mg is an antimalarial medicine primarily used for the radical cure of Plasmodium vivax and Plasmodium ovale malaria. These types of malaria can remain dormant in the liver and cause relapses weeks or months after the initial infection. Primaquine helps eliminate these dormant liver forms, preventing future attacks. It is also used for terminal prophylaxis (prevention) of malaria in individuals who have been exposed to infected mosquitoes. This medicine is often used in combination with other antimalarials like chloroquine to ensure complete treatment.
How Primaquine Phosphate Tablets IP 7.5 mg works
Primaquine belongs to a class of drugs called 8-aminoquinolines. It works by generating reactive oxygen species and interfering with the parasite's mitochondrial function, ultimately killing the malaria parasites. Unlike other antimalarials that target the blood stage, primaquine is effective against the hypnozoites (dormant liver forms) of P. vivax and P. ovale. By clearing these liver stages, it prevents relapses and helps achieve a complete cure.
Common side effects of Primaquine Phosphate Tablets IP 7.5 mg
While primaquine is generally well-tolerated, some individuals may experience side effects. Common ones include:
- Nausea or vomiting
- Abdominal cramps
- Headache
- Dizziness
- Darkening of urine (may indicate a serious condition)
- Methemoglobinemia (bluish skin or lips, shortness of breath)
It is important to note that primaquine can cause hemolytic anemia in individuals with G6PD deficiency. Therefore, a G6PD test is mandatory before starting treatment.
Expert advice for Primaquine Phosphate Tablets IP 7.5 mg
- G6PD testing is essential: Never take primaquine without knowing your G6PD status. If you have G6PD deficiency, your doctor may adjust the dose or choose an alternative.
- Take with food: To reduce stomach upset, take primaquine with meals or milk.
- Complete the full course: Even if you feel better, finish the entire prescribed course to prevent relapse.
- Stay hydrated: Drink plenty of fluids to help your kidneys eliminate the drug and its byproducts.
- Monitor for signs of hemolysis: If you notice dark urine, yellowing of eyes or skin, or unusual tiredness, seek medical help immediately.
- Avoid alcohol: Alcohol may increase the risk of liver toxicity.
- Inform your doctor about all medications: Primaquine may interact with other drugs, including quinine and other antimalarials.
Jan Aushadhi price and availability
Primaquine Phosphate Tablets IP 7.5 mg is available at Jan Aushadhi Kendra stores across India under the Pradhan Mantri Jan Aushadhi Yojana (PMJAY). The MRP for a strip of 10 tablets is ₹12.19, making it an affordable option compared to branded alternatives. The Jan Aushadhi generic medicine is bioequivalent to branded versions and meets quality standards set by the Bureau of Indian Standards (BIS). You can locate your nearest Jan Aushadhi Kendra on the official PMBJP website or app.
Safety note
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified doctor or pharmacist before taking any medicine. Verify the composition, strength, and suitability of this medicine for your condition. Do not self-medicate. If you experience any severe side effects, seek immediate medical attention.