Pemetrexed Injection IP 100 mg Uses
Pemetrexed is a chemotherapy medication used primarily in the treatment of certain types of lung cancer, specifically non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma. It is often used in combination with other anticancer drugs like cisplatin. Pemetrexed works by interfering with the growth and spread of cancer cells in the body.
How Pemetrexed works
Pemetrexed belongs to a class of drugs called antifolates. It inhibits multiple enzymes involved in folate metabolism, including thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase. By disrupting the synthesis of DNA and RNA, pemetrexed prevents cancer cells from multiplying and eventually leads to their death.
Common side effects of Pemetrexed
- Nausea and vomiting
- Fatigue or weakness
- Loss of appetite
- Low blood cell counts (anemia, neutropenia, thrombocytopenia)
- Mouth sores or ulcers
- Skin rash
- Diarrhea or constipation
- Shortness of breath
Expert advice for Pemetrexed
Pemetrexed is a potent chemotherapy drug that must be administered under the supervision of a qualified oncologist. Patients should be premedicated with folic acid and vitamin B12 to reduce toxicity. Regular blood tests are necessary to monitor blood cell counts and kidney function. Inform your doctor about all other medications you are taking, as some may interact with pemetrexed. Do not receive any vaccines without your doctor's approval during treatment.
Jan Aushadhi price and availability
Pemetrexed Injection IP 100 mg is available at Jan Aushadhi Kendras under the Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP). The MRP for this Jan Aushadhi generic medicine is ₹759.38 per vial, which is significantly lower than many branded alternatives. This makes it an affordable option for patients undergoing cancer treatment. Always verify the composition and strength with your doctor or pharmacist before use.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Pemetrexed should only be used under strict medical supervision. Do not self-administer or change your treatment regimen without consulting your healthcare provider. Pemetrexed can cause serious side effects, including severe bone marrow suppression and kidney damage. Pregnant or breastfeeding women should not use this medicine.