Colistimethate Sodium for Injection IP 4.5 Million IU Uses
Colistimethate Sodium for Injection is a powerful antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria, including Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. It is typically reserved for infections that do not respond to other antibiotics, such as hospital-acquired pneumonia, bloodstream infections, and complicated urinary tract infections. This medicine is administered intravenously or intramuscularly under strict medical supervision.
How Colistimethate Sodium for Injection works
Colistimethate Sodium belongs to the polymyxin class of antibiotics. It works by binding to the bacterial cell membrane, disrupting its structure and increasing permeability. This leads to leakage of essential cellular contents and ultimately bacterial death. It is bactericidal against susceptible Gram-negative bacteria.
Common side effects of Colistimethate Sodium for Injection
- Nephrotoxicity (kidney damage) – increased creatinine, decreased urine output
- Neurotoxicity – dizziness, numbness, tingling, slurred speech, muscle weakness
- Allergic reactions – rash, itching, fever
- Gastrointestinal disturbances – nausea, vomiting
- Pain or redness at injection site
Expert advice for Colistimethate Sodium for Injection
- This medicine is given only in a hospital setting under close medical supervision.
- Kidney function must be monitored regularly during treatment.
- Inform your doctor if you have any pre-existing kidney disease or neuromuscular disorders.
- Do not exceed the prescribed dose or duration.
- Report any signs of neurotoxicity (e.g., tingling, weakness) immediately.
Jan Aushadhi price and availability
Colistimethate Sodium for Injection IP 4.5 Million IU is available at Jan Aushadhi Kendras across India at an affordable price of ₹421.88 per vial (10 ml). This generic version offers the same quality and efficacy as branded alternatives but at a fraction of the cost. Always verify the composition and strength with your doctor or pharmacist before use.
Safety note
This information is for educational purposes only and does not replace professional medical advice. Colistimethate Sodium is a potent antibiotic with significant side effects and should only be used under the supervision of a qualified healthcare provider. Do not self-medicate. Always consult your doctor for proper diagnosis and treatment.