Drug Code: 1846 Ortho

Zoledronic Acid Injection IP 4 mg per vial

Product Details

  • Unit Size 4mg/vial
  • Jan Aushadhi MRP ₹200.00
  • Last Updated August 6, 2026
  • Data Source PMBJP Official Drug Database

Zoledronic Acid Injection IP 4 mg per vial Uses

Zoledronic acid injection is a medication primarily used to treat and prevent bone problems in adults. It belongs to a class of drugs called bisphosphonates. This injection is commonly prescribed for conditions such as:

  • Osteoporosis: It helps strengthen bones and reduce the risk of fractures, especially in postmenopausal women and men at high risk.
  • Paget's disease of bone: It helps regulate abnormal bone turnover and reduce bone pain.
  • Hypercalcemia of malignancy: It lowers high blood calcium levels caused by cancer.
  • Multiple myeloma and bone metastases: It helps prevent bone complications like fractures and spinal cord compression in certain cancers.

This medicine is usually given as an intravenous infusion in a hospital or clinic setting. It is not a painkiller but works to improve bone health over time.

How Zoledronic Acid works

Zoledronic acid works by inhibiting the activity of osteoclasts, the cells responsible for breaking down bone tissue. By slowing this process, it helps maintain bone density and strength, reduces bone turnover, and lowers the risk of fractures. It also helps in reducing calcium release from bones into the blood, which is beneficial in conditions like hypercalcemia.

Common side effects of Zoledronic Acid

Like all medicines, zoledronic acid can cause side effects, although not everyone gets them. Common side effects may include:

  • Flu-like symptoms such as fever, chills, muscle aches, and fatigue, especially after the first dose
  • Nausea, vomiting, or diarrhea
  • Headache or dizziness
  • Pain at the injection site
  • Low blood calcium levels (hypocalcemia), which may cause muscle spasms or tingling

Serious side effects are rare but can include kidney problems, jaw bone issues (osteonecrosis of the jaw), or unusual thigh bone fractures. Seek immediate medical help if you experience severe bone, joint, or jaw pain, or signs of an allergic reaction.

Expert advice for Zoledronic Acid

  • This injection is given by a healthcare professional, usually once a year for osteoporosis or as directed by your doctor.
  • Before receiving this medicine, tell your doctor if you have kidney disease, low calcium levels, or dental problems.
  • You may need to have blood tests to check your kidney function and calcium levels before and after treatment.
  • Stay well hydrated before and after the infusion to reduce the risk of kidney side effects.
  • Take calcium and vitamin D supplements as recommended by your doctor to support bone health.
  • Inform your dentist that you are receiving zoledronic acid before any dental procedures.

Jan Aushadhi price and availability

At Jan Aushadhi Kendra, Zoledronic Acid Injection IP 4 mg per vial is available at an affordable price of ₹200 per vial. This generic version offers the same quality and effectiveness as more expensive branded alternatives, making it a cost-effective choice for patients. You can find this medicine at your nearest Jan Aushadhi store. Always verify the composition and strength with your doctor or pharmacist before use.

Safety note

This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before using any medicine. Do not self-medicate. Ensure that the medicine is prescribed for your specific condition and that you understand the correct dosage and administration. If you experience any unusual symptoms after receiving this injection, contact your healthcare provider immediately.

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Known Brand Alternatives

This Jan Aushadhi medicine is a generic equivalent for:

Zometa Aclasta Zoledronic Zolaxa Zoldria Zoledron

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Frequently Asked Questions

What is the Jan Aushadhi price of Zoledronic Acid Injection 4mg?

The Jan Aushadhi price of Zoledronic Acid Injection IP 4mg per vial is ₹200. This is significantly lower than many branded versions, making it an affordable option for patients. However, always confirm the current price at your local Jan Aushadhi Kendra.

How often is Zoledronic Acid injection given?

The frequency of Zoledronic Acid injection depends on the condition being treated. For osteoporosis, it is often given once a year. For other conditions like Paget's disease or cancer-related bone issues, the schedule may differ. Your doctor will determine the appropriate dosing interval based on your health needs.

Can I take Zoledronic Acid if I have kidney problems?

Zoledronic Acid is not recommended for people with severe kidney impairment. Your doctor will assess your kidney function before prescribing this medicine. If you have mild to moderate kidney issues, your doctor may adjust the dose or monitor you closely. Always discuss your medical history with your doctor.

Are there any dietary supplements I should take with Zoledronic Acid?

Yes, your doctor may recommend calcium and vitamin D supplements to help maintain bone health while on Zoledronic Acid. This is especially important because the medicine can lower blood calcium levels. Follow your doctor's advice on dosage and duration.

Disclaimer: Information is for educational and reference purposes only. Always consult a qualified doctor or pharmacist before changing medicines. Do not replace prescribed medicines without medical advice.

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